I am not a doctor, or a nurse, or a pharmacist, but could someone explain to me how this combination, given all together over such a short weekend, is a good thing?
*edit* I mean, I'm well aware that Zinc, Vitamin D, and Melatonin were likely administered in his daily Centrum Silver tablet, but the rest.
https://twitter.com/RVAwonk/status/1312827046825992192
It's a slow night so here's my $0.02
Remdesivir:
An antiviral agent. Not FDA approved but showed enough shortening of the duration of COVID related illness in the approval trials that the FDA allowed Emergency Use Authorization. Minimal side effects are listed.
Regeneron:
Handy is correct. This is reportedly a cocktail of recombinant antibodies being used to boost ones own antibody response to virus. Similar to the practice of transfusing plasma to the Pt from those who have already survived the infection. This has anecdotally been beneficial and the recombinant approach theoretically might eliminate some of the risks involved with a transfusion of any type. Experimental and unavailable to the public. As such, little is known about it. Apparently it is early on in the trials but theoretically could be very useful. Side effects and risks are known only to the company.
Dexamethasone:
A steroid that has proven to decrease 28 day mortality rate. Thought to diminish the "Hyper-immune Response" that many feel is one of, if not the main reason COVID is so lethal.
Oxygen:
This requires no explanation. Things go better with O2. (However, too much O2, if it is not necessary, can actually be a bad thing.)
Zinc/Vitamin D/Melatonin:
These are supplements that, IMO, are in the "chicken soup" category. They can't hurt. Zinc deficiency is thought by some to be a risk factor for developing viral infections and has been thought to decrease cold Sx. Pt's with sufficient Vitamin D reportedly have less complications than those with a Vitamin D deficiency. I am unaware of anything showing that supplements help in Pt's with adequate levels. Melatonin is reportedly an anti-inflammatory and has been shown to limit viral-related diseases and may help here. There are no formal studies that have been done (that I'm aware of) that have shown benefits in it's use with COVID. All that being said, using these meds has little to no risk and some theoretical benefit. Why not give them a try.
Famotidine:
This is a H2-antagonist used to decrease stomach acid. The "H" is Histamine that also has a role in the immune response and has been shown to be associated with less deaths in Pt's receiving this than those not receiving it. Once again the reason is thought to be a blunting of the so-called "Hyper-immune Response".
ASA:
I assume this is to help with a possible hypercoagulable state. I'm unaware of studies proving it's benefit with COVID, but again, a low risk/high potential reward scenario
Why is tDonald getting all these? He may be much sicker than they are letting on or they be empirically "blasting" him with all they have in order to try and stop progression to a severe case. Your guess is as good as mine. Based on his recent drive by, I am assuming a little bit of both more of the later.
As far as the "drive by" is concerned. Any competent Patient* can leave the hospital at any time they choose. Any competent Pt can choose not to follow their Physicians advice. There is little doubt in my that his Physician told him that he shouldn't do the drive by but it is his right to ignore that advice. Even in a quarantine situation, the doctor can't keep a competent Pt in the hospital against their will. I believe that the physician could contact the health dept. who then in turn could issue a warrant for the Pt's arrest for endangering others but they can't force him to stay. FWIW, malpractice has absolutely nothing to do with this scenario.
* The argument concerning tDonald's overall competency is clearly a matter of perspective but there is little question that he currently be deemed competent enough to be allowed to make his own medical decisions
ETA:
GET YOUR FLU VACCINE!!!!! ALL OF YOU