I've worked a few hundred-hour weeks in my career. But in every case, I was on business travel to a site where a developmental airplane needed to be fixed so that it could go fly to resume a military or FAA certification campaign. When a company has $10B wrapped up in a project and can't get paid until it completes, you work. When there are 500 people supporting flight testing who literally cannot do their jobs until your part is fixed, you work. That's just the nature of working on a system with 1000's of critical parts. If any one of them is broken and delaying the project, it needs to be fixed right freaking now.
But it's one thing to do that when you're on business travel, staying in a hotel with housekeeping and room service and dry cleaning and driving a rental car that needs no maintenance. You literally have nothing to do except work - no errands, no spouse, no kids, no dishes to do, and you know that it is temporary. Doing that at home for 2 years straight as part of a "normal" work routine? Hell, no. Not an option.