There are (currently) only three components to a Pairwise comparison: RPI, head-to-head, and common opponents.
'Common Opponents' comparison only results in a "plus one" for whichever team "wins" that component of a pairing. Likewise RPI. So if there are no head-to-head games between the two teams being compared, the only outcomes are one team is better at both 'common opponents' and RPI and wins the comparison "two to zero", or they split and the comparison is "one to one tie". And that tie is broken by whoever has the better RPI wins the comparison.
That is to say, unless the two teams have a head-to-head, whoever has the better RPI wins the comparison. Period, the end. And more "interconference games played" won't change that.
"More games" would only help those Pairwise comparisons if it added a head-to-head component to the comparison, and how many games would you have to add to get the point where there are enough head-to-heads to make a difference? Likely lots more than you have weekends available.
(One example of a head-to-head making a difference in the Pairwise this year is Duluth having swept Harvard. Right now Harvard has a SLIGHTLY better RPI, but Duluth is winning the comparison on the strength of being "plus two" in head-to-head. On the other hand, Wisconsin's head-to-head vs Quinnipiac ends up NOT being significant in their comparison, because they simply have no "common opponents". Wisconsin had a win and a tie vs Quinnipiac, and so are "plus one" head-to-head; but with no common opponents, if Quinnipiac were to end up with a better RPI, the better RPI would once again win them the comparison.)
Pretty much the only way to have the Pairwise be little more that a reproduction of the RPI list, and get more 'mixing' as a result of the comparisons (assuming such 'mixing' would be a good thing and lead to a better tournament, and I'm not at all convinced that would be the case) would be one or more additional components to a Pairwise comparison, such as the "teams under consideration" component that used to be there. And I don't have any ideas on what that might be. They got rid of "TUC" for a reason, and i don't know that anyone would want to bring it back.
If you ask me, they could pretty much do away with the Pairwise altogether, and just use RPI. (Or use KRACH, etc, instead). You'll get essentially the same tournament field anyway.
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Adding, so maybe your question should be "would more interconference play help the 'validity' of the RPI?", and the answer to that is absolutely yes.