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Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

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  • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

    "It's as if the Drumpf Administration is made up of the worst and unfunny parts of the Cleveland Browns, Washington Generals, and the alien Mon-Stars from Space Jam."
    -aparch

    "Scenes in "Empire Strikes Back" that take place on the tundra planet Hoth were shot on the present-day site of Ralph Engelstad Arena."
    -INCH

    Of course I'm a fan of the Vikings. A sick and demented Masochist of a fan, but a fan none the less.
    -ScoobyDoo 12/17/2007

    Comment


    • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

      Originally posted by Handyman View Post
      Get on the snake with a swarm of motor flies
      Get on the snake under the cola-colored sky
      No don't worry, everything's clean
      Road worthy, hungry and mean

      Comment


      • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

        Houston looks like they may be in trouble soon. We had the most cases here in Dallas County for most of March. Harris (Houston) overtook us a week ago and will soon double the amount of cases as we do. Currently, 2146 to 1261.
        Jordan Kawaguchi for Hobey!!
        Originally posted by Quizmire
        mns, this is why i love you.

        Originally posted by Markt
        MNS - forking genius.

        Originally posted by asterisk hat
        MNS - sometimes you gotta answer your true calling. I think yours is being a pimp.

        Originally posted by hockeybando
        I am a fan of MNS.

        Comment


        • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

          Originally posted by wolverineTrumpet View Post
          Well, I came into work today and have been useless since getting here.

          They set up a temperature screening outside, so you can't come in the building if you have a fever, or answer wrong to the screening questions.

          My temperature reading was 99.5. You're allowed in as long as you're under 100.4. I know that I usually read low, like 97.9-98.3. So now I don't know if I have a fever, or it's just a not so accurate thermometer, the heat was on in my car (it's a drive through screening), etc.
          Either way I'm paranoid and interpreting everything as a possible symptom, maybe thinking myself into feeling symptoms. Meanwhile I was cleared to enter the building, but I'm spending a lot of time wondering if I should go home.

          Doing my best to keep any potential germs to myself.
          Surprised no one answered this before. YOU DO NOT HAVE A FEVER! am a little late but... Here is the canned speech I gave for years-

          Human average temperature is 98.6.
          On avg men tend to run higher than women
          It is not unusual for women to run slightly lower but if you were to monitor over time the temp goes up and down. Women's temps can be dependent on the time in their cycle. THink natural family planning temperature to predict ovulation.
          All people- temperature goes up and down dependent on time of day
          Temps can be taken different ways. Depending on the site temp is taken fever may be defined differently
          Rectal, ear or temporal artery temperature of 100.4 (38 C) or higher. Oral temperature of 100 F (37.8 C) or higher. Armpit temperature of 99 F (37.2 C) or higher.
          Your average temperature has nothing to do with what is considered a fever.
          No matter what you usually run for a temp the definition of fever is based on what happens in the body at temperatures considered 'fever'~When you have a 'fever' it sets off a whole bunch of things in the body's immune system.

          So, we have flown by 12K. A month ago someone 'bet me' that there would not even be 12K deaths. I shouldn't argue with him because he is a numbers guy and he worked out the stats. Of course he had no clue it is different to predict disease than some sort of mechanical thing. I told him he was wrong and why I thought so. He bet me a beer and called me chicken if I didn't bet. Here we are. 12K and not even really getting started. It is taking everything in me not to message him and say I don't drink beer but maybe instead he could realize that Public Health isn't something he knows enough about to make assumptions and tell someone who has some training that they don't know anything. I don't have the energy.

          DOn't think I have seen this posted here- Dr Fauci in 2017 talking about what is happening now https://www.yahoo.com/huffpost/fauci...200054359.html

          Long but good

          Comment


          • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.



            It is amazing how effective your treatment can be when you dont count those that didnt improve in the results
            "It's as if the Drumpf Administration is made up of the worst and unfunny parts of the Cleveland Browns, Washington Generals, and the alien Mon-Stars from Space Jam."
            -aparch

            "Scenes in "Empire Strikes Back" that take place on the tundra planet Hoth were shot on the present-day site of Ralph Engelstad Arena."
            -INCH

            Of course I'm a fan of the Vikings. A sick and demented Masochist of a fan, but a fan none the less.
            -ScoobyDoo 12/17/2007

            Comment


            • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

              I’ve been saying that for a week plus now. That study was outright fraud.

              Originally posted by SJHovey View Post
              Walz will apparently ease restrictions in Minnesota tomorrow.
              I highly doubt this.

              What restrictions?
              Code:
              As of 9/21/10:         As of 9/13/10:
              College Hockey 6       College Football 0
              BTHC 4                 WCHA FC:  1
              Originally posted by SanTropez
              May your paint thinner run dry and the fleas of a thousand camels infest your dead deer.
              Originally posted by bigblue_dl
              I don't even know how to classify magic vagina smoke babies..
              Originally posted by Kepler
              When the giraffes start building radio telescopes they can join too.
              He's probably going to be a superstar but that man has more baggage than North West

              Comment


              • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

                Copied from the D1 thread.

                Originally posted by SteveO View Post
                My post regarding an RCT that is currently being conducted under the leadership of a colleague, Dr. Dave Boulware, is "pimping" HCQ? I don't have any axe to grind here, but apparently you do.

                If you want to falsely accuse US healthcare professionals as well as those around the globe (India, Germany, France, etc.) who are currently administering HCQ/AZ to CoV-19 patients with measured success of "pimping" that's entirely up to you. Go ahead and embarrass yourself.
                I think they're being irresponsible, yes. But only one of us is embarrassing himself. Are you going to point to controlled studies these doctors are conducting with results? Or just anecdotal reports from Hannity and Dr. Oz?

                Originally posted by SteveO View Post
                It's noteworthy that Kansas City area physicians. as well as others in several states are continuing to treat CoV-19 patients with HCQ/AZ and are showing marked improvement in the reduction of the viral load. Major medical centers including the University of Washington and Mass General have added HCQ to treatment options. Other state pharmacy boards including Texas, Louisiana, Ohio and North Carolina have approved its use under physician care by prescription only which prevents individuals from misusing the drug by self-medicating.
                Really? They are? Where's the data? What are the study parameters? I'm sure you have those links handy, especially using words like "marked improvement". Because normally we leave words like "marked improvement" to the marketing departments.

                State pharmacy boards approving a drug to be used only means nothing without data. It doesn't mean there's evidence of efficacy, only that we're in a pandemic emergency and we're desperate and making ill-informed decisions based on anecdotal data. We don't know if the drugs are effective, we don't know what the side-effects are, and I'm not sure we have anything close to informed consent.

                Originally posted by SteveO View Post
                Yesterday the FDA and The Department of Health and Human Services (HHS) approved HCQ products to be distributed and prescribed by doctors through the Strategic National Stockpile to hospitalized teen and adult patients with CoV-19 as appropriate.

                HHS said Germany’s Sandoz has already given 30 million doses of HCQ to the Strategic National Stockpile, and Bayer has donated a million doses. Pfizer has announced positive data for the use HCQ/AZ in an RCT recently completed in Marseille, France (see below).
                I wouldn't bother quoting the studies out of Marseille. They're wrought with bad science, they're limited in scope, and have dubious conclusions. Regarding donations, those are politically and likely financially motivated decisions. Not evidence of anything resembling science.

                Originally posted by SteveO View Post
                I'd like to see the evidence to confirm your accusation that Dr. Didier Raoult MD. PhD. is a "fraud". Arguably, his previous small study raised some concerns on the research design side. But Dr. Raoult was officially a member of the first scientific council set up by French President Macron to advise him on the CoV-19 pandemic. He's definitely NOT a fraud.
                Wildcard already posted links showing Raoult photoshopped gels and other stains. Literally copied and pasted. It was obvious. He was even banned from publishing in the American Society of Microbiology for a year because of his fraud. There are six separate cases of questionable data in his papers that look like outright fraud.

                Originally posted by SteveO View Post
                In fact, Dr. Raoult and a collaborative team of 28 microbiologists, physicians, biostatisticians, and pharmacologists in Marseille just completed and published the largest RCT to date last week on March 27 involving 80 CoV-19 patients who were treated with HCQ/AZ. The study was conducted at the University Hospital Institute Méditerranée Infection in Marseille, France and financially supported by the French National Research Agency.
                And it's already being skewered for many of the same reasons the original study was.

                Originally posted by SteveO View Post
                The median age was 52 years (range 20 to 86) with nearly 1:1 male/female. The primary therapeutic objective was to treat patients who have moderate or severe infections at an early enough stage to avoid progression to a serious and irreversible condition. The elimination of viral carriage in the human reservoir of the virus was recognized in the study as a priority.

                57.5% of the patients had at least one chronic condition known to be a risk factor for the severe form of CoV-19 with hypertension, diabetes and chronic respiratory disease being the most frequent. The mean Polymerase chain reaction (PCR) (a method used to copy and amplify specific DNA samples for detailed analysis) CT value was 23.4. A PCR CT value < 34 means the patient has tested positive for CoV-19.
                No, it means that test did not detect enough of the markers to be considered positive. It doesn't mean the patient is negative or positive or that they weren't going to be shedding the virus through other means. More on this in a second.

                Also, if the study was to look at preventing the progression of the disease to severe, it seems fairly odd to remove people who died or progressed to the ICU from the study's results.

                Originally posted by SteveO View Post
                A rapid fall of nasopharyngeal viral load tested by PCR was noted, with 83% negative at Day 7, and 93% at Day 8. The number of patients presumably contagious (with a PCR CT value <34) steadily decreased overtime and reached zero on Day 12.
                Hey, that's great! I'm hoping you can explain this then:

                From the Lancet, a journal with some actual credibility.

                You'll note that throat swab PCR tests come back negative after a mean of 16.7 days after first symptom onset. Also worth noting the French study doesn't discuss time from first onset of symptoms (they even included four people who were asymptomatic!) to negative tests. In the Lancet study, the fecal tests come back positive an average of 10+ days after the throat swabs are negative. Just because the PCR tests from one sampling method came back negative doesn't mean the patients had an outcome different than the natural progression of the disease.

                It would have also been more helpful if the French study had discussed the sensitivity of the testing methods and whether false positives and negatives could influence the results. But, alas, they didn't.

                Another great article I read by Derek Lowe asked why a simple cutoff of Ct <34 was used instead of tracking actual patient tracking in the larger study. Of those that were still positive on subsequent days, did they get worse? Slightly better? Much better? We just don't know because they don't include the full data for each patient, just aggregated.

                The article also questions the methodology. Of the 80 that we’re <34 Ct on Day 0, on Day 1 only 70 tested positive? That would mean the treatment worked overnight on ten? Presumably the professor would claim they were from the 49, but we don’t know because he didn’t think it important to include that data. I’m skeptical at best. The article goes on to question why we aren’t seeing individual patient data for PCR counts instead of aggregated data which really doesn’t tell us anything. Why not look at whether viral loads were actually decreased at a quicker rate than the control group?

                There was also some interesting discussion of their testing methods on PubPeer (link)

                1/2 - Cont'd
                Code:
                As of 9/21/10:         As of 9/13/10:
                College Hockey 6       College Football 0
                BTHC 4                 WCHA FC:  1
                Originally posted by SanTropez
                May your paint thinner run dry and the fleas of a thousand camels infest your dead deer.
                Originally posted by bigblue_dl
                I don't even know how to classify magic vagina smoke babies..
                Originally posted by Kepler
                When the giraffes start building radio telescopes they can join too.
                He's probably going to be a superstar but that man has more baggage than North West

                Comment


                • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

                  Cont'd (2/2)

                  Originally posted by SteveO View Post
                  The team concluded that the rapid negativation of viral cultures from patients’ respiratory samples under treatment with HCQ/AZ showed the efficacy of the HCQ/AZ dyad. Moreover, the rapid decrease in the viral RNA load also suggests the effectiveness of the treatment in the early impairment of contagiousness.
                  Even The Simpsons gets what you and the French team don't. Without randomized, blind control data you can claim anything helps with a small enough study.

                  Most telling, 85% of his study patients didn’t even have a fever. Doesn’t that strike you as an astonishing figure given that 90-95% or more of hospitalized patients have a fever? He somehow picked the most severe patients when they didn’t even have a fever? That’s... remarkable!! Crazier still, four people in his follow-up were asymptotic entirety. Doesn’t that kind of make you wonder how or why they’re even being studied? Then he excluded from the results the patients who transferred to the ICU or died?

                  You might claim (actually, I think you did above) that this was meant to show that this helps protect people from getting worse. Without a control, you can't claim that either way.

                  Originally posted by SteveO View Post
                  And finally, my favorite. I'm glad you included this because it goes along with your flamboyant language and lack of understanding. It sure looks pretty, but it doesn't really say what you think it does.

                  First, why would they use a quadratic regression in this graph and an exponential regression in the other graph they've published? I mean, this is kind of crazy. That’s the kind of thing a moron who doesn’t understand stats does. As one of the articles about this study said, “makes for great R-squared numbers!” The average idiot who uses Excel, me and apparently you, just click through the regressions without any reasoning behind why you'd use one or the other, until you find a great R2 number. That's not how science works. You state a theory, test the theory, if it comes back right, great! If it doesn't, you conduct more experiments with another hypothesis and either reject or accept it. You don't hunt for numbers that fit your conclusion. That's not how the scientific method works. He might as well have sharpied that trend line in and wrote "Alabama!"

                  I'll also add this:
                  https://scienceintegritydigest.com/2...19-infections/. The article does a fantastic job detailing the bad science, questionable ethics, and conflicts of interest Professor Raoult's paper was riddled with.

                  The other thing I question is whether the drugs are just messing with the test. Did the patients actually get better? What were their outcomes? Or was it just that the natural progression was their PCR counts crossed the 34 threshold.

                  Post all of the cute graphs, numbers, and intelligent sounding jargon you want, it doesn’t show what you think it does. People get better over time spontaneously without intervention. We don’t have any data. The guy is a bad scientist at best or a fraud at worst. Even reading through the paper you should have been immediately skeptical. That you weren’t makes me wonder why.
                  Code:
                  As of 9/21/10:         As of 9/13/10:
                  College Hockey 6       College Football 0
                  BTHC 4                 WCHA FC:  1
                  Originally posted by SanTropez
                  May your paint thinner run dry and the fleas of a thousand camels infest your dead deer.
                  Originally posted by bigblue_dl
                  I don't even know how to classify magic vagina smoke babies..
                  Originally posted by Kepler
                  When the giraffes start building radio telescopes they can join too.
                  He's probably going to be a superstar but that man has more baggage than North West

                  Comment


                  • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

                    "It's as if the Drumpf Administration is made up of the worst and unfunny parts of the Cleveland Browns, Washington Generals, and the alien Mon-Stars from Space Jam."
                    -aparch

                    "Scenes in "Empire Strikes Back" that take place on the tundra planet Hoth were shot on the present-day site of Ralph Engelstad Arena."
                    -INCH

                    Of course I'm a fan of the Vikings. A sick and demented Masochist of a fan, but a fan none the less.
                    -ScoobyDoo 12/17/2007

                    Comment


                    • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

                      Uh dx...there is a reason a lot of us avoid those clowns like the plague.
                      "It's as if the Drumpf Administration is made up of the worst and unfunny parts of the Cleveland Browns, Washington Generals, and the alien Mon-Stars from Space Jam."
                      -aparch

                      "Scenes in "Empire Strikes Back" that take place on the tundra planet Hoth were shot on the present-day site of Ralph Engelstad Arena."
                      -INCH

                      Of course I'm a fan of the Vikings. A sick and demented Masochist of a fan, but a fan none the less.
                      -ScoobyDoo 12/17/2007

                      Comment


                      • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

                        If the incompetence of this administration didn’t kill 2,000 American today, that should be the headline.
                        Code:
                        As of 9/21/10:         As of 9/13/10:
                        College Hockey 6       College Football 0
                        BTHC 4                 WCHA FC:  1
                        Originally posted by SanTropez
                        May your paint thinner run dry and the fleas of a thousand camels infest your dead deer.
                        Originally posted by bigblue_dl
                        I don't even know how to classify magic vagina smoke babies..
                        Originally posted by Kepler
                        When the giraffes start building radio telescopes they can join too.
                        He's probably going to be a superstar but that man has more baggage than North West

                        Comment


                        • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

                          Originally posted by dxmnkd316 View Post
                          If the incompetence of this administration didn’t kill 2,000 American today, that should be the headline.
                          In the next couple days we could be seeing a 9/11 every day...
                          "It's as if the Drumpf Administration is made up of the worst and unfunny parts of the Cleveland Browns, Washington Generals, and the alien Mon-Stars from Space Jam."
                          -aparch

                          "Scenes in "Empire Strikes Back" that take place on the tundra planet Hoth were shot on the present-day site of Ralph Engelstad Arena."
                          -INCH

                          Of course I'm a fan of the Vikings. A sick and demented Masochist of a fan, but a fan none the less.
                          -ScoobyDoo 12/17/2007

                          Comment


                          • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

                            Originally posted by Handyman View Post
                            Uh dx...there is a reason a lot of us avoid those clowns like the plague.
                            I know. That was a human equivalent of an x-class flare.

                            An instantaneous release of hundreds of overstressed and tangled lines all at once. Something kind of snapped and I couldn’t take it anymore.
                            Code:
                            As of 9/21/10:         As of 9/13/10:
                            College Hockey 6       College Football 0
                            BTHC 4                 WCHA FC:  1
                            Originally posted by SanTropez
                            May your paint thinner run dry and the fleas of a thousand camels infest your dead deer.
                            Originally posted by bigblue_dl
                            I don't even know how to classify magic vagina smoke babies..
                            Originally posted by Kepler
                            When the giraffes start building radio telescopes they can join too.
                            He's probably going to be a superstar but that man has more baggage than North West

                            Comment


                            • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

                              Originally posted by Handyman View Post
                              In the next couple days we could be seeing a 9/11 every day...
                              Could you imagine a 9/11 a day on Obama’s watch?
                              Code:
                              As of 9/21/10:         As of 9/13/10:
                              College Hockey 6       College Football 0
                              BTHC 4                 WCHA FC:  1
                              Originally posted by SanTropez
                              May your paint thinner run dry and the fleas of a thousand camels infest your dead deer.
                              Originally posted by bigblue_dl
                              I don't even know how to classify magic vagina smoke babies..
                              Originally posted by Kepler
                              When the giraffes start building radio telescopes they can join too.
                              He's probably going to be a superstar but that man has more baggage than North West

                              Comment


                              • Re: Covfefe-19 part 6: Waiting For Advice from Kid Rock and Tiger Woods now.

                                Originally posted by dxmnkd316 View Post
                                Could you imagine a 9/11 a day on Obama’s watch?
                                I believe the new Press Secretary said 9/11 was when Obama was in office...

                                (the sad thing is she probably will)
                                "It's as if the Drumpf Administration is made up of the worst and unfunny parts of the Cleveland Browns, Washington Generals, and the alien Mon-Stars from Space Jam."
                                -aparch

                                "Scenes in "Empire Strikes Back" that take place on the tundra planet Hoth were shot on the present-day site of Ralph Engelstad Arena."
                                -INCH

                                Of course I'm a fan of the Vikings. A sick and demented Masochist of a fan, but a fan none the less.
                                -ScoobyDoo 12/17/2007

                                Comment

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