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  • #1

    Covid 2023

    New variant BA.2.86 has a genetic difference from prior strains on par with Omicron.

    The strain's emergence comes as drugmakers have been preparing to roll out new COVID-19 vaccines next month aimed at the XBB strains of the virus, of which EG.5 is closely related. Moderna announced Thursday that its preliminary clinical trial data from the new shots confirmed "a significant boost in neutralizing antibodies" for EG.5.

    Those could face a setback if BA.2.86 is able to spread more widely. Bloom said he thinks the strain's changes are enough to risk making the XBB-targeted vaccines a "fairly poor match" to BA.2.86.

    But he underscored that BA.2.86 remains rare for now, and other defenses mounted by the body may also still work to fend off the highly-mutated variant.
    Cornell University
    National Champion 1967, 1970
    ECAC Champion 1967, 1968, 1969, 1970, 1973, 1980, 1986, 1996, 1997, 2003, 2005, 2010
    Ivy League Champion 1966, 1967, 1968, 1969, 1970, 1971, 1972, 1973, 1977, 1978, 1983, 1984, 1985, 1996, 1997, 2002, 2003, 2004, 2005, 2012, 2014, 2018, 2019, 2020
    Tags: covid, darwin, vaccine
  • #2
    Originally posted by Kepler View Post
    New variant BA.2.86 has a genetic difference from prior strains on par with Omicron.
    I had my annual check up about two weeks ago. My doctor, who is also a personal friend of mine, also works as one of the instructors at the Mayo Clinic. He and I were BSing after he was done poking and prodding me, and he told me that one of his patients is Mayo's chief doctor in charge of covid. He said that doctor had also just been in for an annual check up with him and they got to talking about covid.

    She told him this year's version was going to be "lethal," according to my doctor. My doctor told me to not get a vaccine until very, very late fall, or early winter, even though people are pushing boosters now. He said the vaccines we've already gotten are going to be completely ineffective against what we will see this winter. But he also related that she said the new vaccines they will be coming out with this winter are going to work great. However, Mayo is bracing for a bad winter due to vaccine fatigue, the feeling that people will have that they've already had four or five shots so they should be good, and the fact that the old vaccines will be worthless against the coming strain.

    Take that for what it's worth.
    That community is already in the process of dissolution where each man begins to eye his neighbor as a possible enemy, where non-conformity with the accepted creed, political as well as religious, is a mark of disaffection; where denunciation, without specification or backing, takes the place of evidence; where orthodoxy chokes freedom of dissent; where faith in the eventual supremacy of reason has become so timid that we dare not enter our convictions in the open lists, to win or lose.
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    • #3
      Originally posted by SJHovey View Post

      I had my annual check up about two weeks ago. My doctor, who is also a personal friend of mine, also works as one of the instructors at the Mayo Clinic. He and I were BSing after he was done poking and prodding me, and he told me that one of his patients is Mayo's chief doctor in charge of covid. He said that doctor had also just been in for an annual check up with him and they got to talking about covid.

      She told him this year's version was going to be "lethal," according to my doctor. My doctor told me to not get a vaccine until very, very late fall, or early winter, even though people are pushing boosters now. He said the vaccines we've already gotten are going to be completely ineffective against what we will see this winter. But he also related that she said the new vaccines they will be coming out with this winter are going to work great. However, Mayo is bracing for a bad winter due to vaccine fatigue, the feeling that people will have that they've already had four or five shots so they should be good, and the fact that the old vaccines will be worthless against the coming strain.

      Take that for what it's worth.
      Thank you, that is good information.

      I wonder, though, if the new booster is not a good match for the new strain does that also mean the booster for the new strain will not be a good match for the existing strains, so we should get both anyway? Or do the boosters just keep aggregating in coverage?

      This is important for me to understand because Dr. Mrs. has a compromised immune system (MS) and she is high vulnerability.
      Last edited by Kepler; 08-18-2023, 09:02 AM.
      Cornell University
      National Champion 1967, 1970
      ECAC Champion 1967, 1968, 1969, 1970, 1973, 1980, 1986, 1996, 1997, 2003, 2005, 2010
      Ivy League Champion 1966, 1967, 1968, 1969, 1970, 1971, 1972, 1973, 1977, 1978, 1983, 1984, 1985, 1996, 1997, 2002, 2003, 2004, 2005, 2012, 2014, 2018, 2019, 2020

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      • #4
        Originally posted by Kepler View Post

        Thank you, that is good information.

        I wonder, though, if the new booster is not a good match for the new strain does that also mean the booster for the new strain will not be a good match for the existing strains, so we should get both anyway? Or do the boosters just keep aggregating in coverage?

        This is important for me to understand because Dr. Mrs. has a compromised immune system (MS) and she is high vulnerability.
        The way I interpreted his message, at least for me, was this. Don't get the current booster now because I'm going to want to get the new one in say November or early December, and if I get one now at the first of September, it might be too early for me in November.

        He asked when I had my last one (#5 for those keeping score at home), and it was in February. His response was that this would be the normal time where I would get another, but he didn't want me to because of the change in strain.

        That community is already in the process of dissolution where each man begins to eye his neighbor as a possible enemy, where non-conformity with the accepted creed, political as well as religious, is a mark of disaffection; where denunciation, without specification or backing, takes the place of evidence; where orthodoxy chokes freedom of dissent; where faith in the eventual supremacy of reason has become so timid that we dare not enter our convictions in the open lists, to win or lose.

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        • #5
          Good to know. I was going to get my booster in Oct along with flu and pneumonia and now RSV.
          A bad cause requires many words.

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          • #6
            Originally posted by SJHovey View Post

            The way I interpreted his message, at least for me, was this. Don't get the current booster now because I'm going to want to get the new one in say November or early December, and if I get one now at the first of September, it might be too early for me in November.

            He asked when I had my last one (#5 for those keeping score at home), and it was in February. His response was that this would be the normal time where I would get another, but he didn't want me to because of the change in strain.
            I haven't had a booster since last Fall. The perils of being one of the first to hit for the cycle is nothing since.
            Cornell University
            National Champion 1967, 1970
            ECAC Champion 1967, 1968, 1969, 1970, 1973, 1980, 1986, 1996, 1997, 2003, 2005, 2010
            Ivy League Champion 1966, 1967, 1968, 1969, 1970, 1971, 1972, 1973, 1977, 1978, 1983, 1984, 1985, 1996, 1997, 2002, 2003, 2004, 2005, 2012, 2014, 2018, 2019, 2020

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            • #7
              Will wait with the booster then, anyway i have a lot of things to do these days.
              Was concentrated on reading about academic writing here https://academized.com/ these days as i am thinking to apply for second degree.
              I am not sure that i can actually manage it, but i guess only the time will show me that. Hope for the best .
              Last edited by anygreen; 08-22-2023, 04:09 PM.

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              • #8
                Originally posted by SonofSouthie View Post
                Good to know. I was going to get my booster in Oct along with flu and pneumonia and now RSV.
                That was the other thing he said. He really pushed me to get the RSV shot this fall.
                That community is already in the process of dissolution where each man begins to eye his neighbor as a possible enemy, where non-conformity with the accepted creed, political as well as religious, is a mark of disaffection; where denunciation, without specification or backing, takes the place of evidence; where orthodoxy chokes freedom of dissent; where faith in the eventual supremacy of reason has become so timid that we dare not enter our convictions in the open lists, to win or lose.

                Comment

                • #9
                  Originally posted by anygreen View Post
                  Will wait with the booster then
                  Well you should just update your anti-virus protection each week when that reminder pops up.

                  Cornell '04, Stanford '06

                  KDR

                  Rover Frenchy, Classic! Great post.
                  iwh30 I wish I could be as smart as you. I really do you are the man
                  gregg729 I just saw your sig, you do love having people revel in your "intelligence."
                  Ritt18 you are the perfect representation of your alma mater.
                  Miss Thundercat That's it, you win.
                  TBA#2 I want to kill you and dance in your blood.
                  DisplacedCornellian Hahaha. Thread over. Frenchy wins.

                  Test to see if I can add this.
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                  • #10
                    Covid is most definitely surging in New England, but hospital censuses are not. This is a very good thing - when the two rates are aligned we have problems. Also, hopefully, the people getting covid now are less likely to contract it in the fall.


                    That said, I've read similar things about new boosters in terms of target, efficacy and timing. I will wait for my company's ID docs to communicate out recommendations. Until then I'm living my life much like I did pre-covid: avoiding people actively sick and avoiding people if I get sick.
                    I gotta little bit of smoke and a whole lotta wine...
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                    • #11
                      Got my last booster in September 2022. Was planning to get another this month ahead of my trip to Greece next month, but then I got COVID late May so I can't get it now till after I get back.

                      Comment

                      • #12
                        Originally posted by French Rage View Post

                        Well you should just update your anti-virus protection each week when that reminder pops up.
                        Now that Gates put the 4G in us.
                        Cornell University
                        National Champion 1967, 1970
                        ECAC Champion 1967, 1968, 1969, 1970, 1973, 1980, 1986, 1996, 1997, 2003, 2005, 2010
                        Ivy League Champion 1966, 1967, 1968, 1969, 1970, 1971, 1972, 1973, 1977, 1978, 1983, 1984, 1985, 1996, 1997, 2002, 2003, 2004, 2005, 2012, 2014, 2018, 2019, 2020

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                        • #13
                          Originally posted by Kepler View Post

                          Now that Gates put the 4G in us.
                          When I heard the government was putting chips in everyone, I hoped I'd get Doritos Cool Ranch. I was so disappointed I didn't get the Doritos.
                          Facebook: bcowles920 Instagram: missthundercat01
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                          • #14
                            Originally posted by MissThundercat View Post

                            When I heard the government was putting chips in everyone, I hoped I'd get Doritos Cool Ranch. I was so disappointed I didn't get the Doritos.
                            I'd have taken Erik Estrada in me.
                            Cornell University
                            National Champion 1967, 1970
                            ECAC Champion 1967, 1968, 1969, 1970, 1973, 1980, 1986, 1996, 1997, 2003, 2005, 2010
                            Ivy League Champion 1966, 1967, 1968, 1969, 1970, 1971, 1972, 1973, 1977, 1978, 1983, 1984, 1985, 1996, 1997, 2002, 2003, 2004, 2005, 2012, 2014, 2018, 2019, 2020

                            Comment

                            • #15
                              Originally posted by SJHovey View Post

                              I had my annual check up about two weeks ago. My doctor, who is also a personal friend of mine, also works as one of the instructors at the Mayo Clinic. He and I were BSing after he was done poking and prodding me, and he told me that one of his patients is Mayo's chief doctor in charge of covid. He said that doctor had also just been in for an annual check up with him and they got to talking about covid.

                              She told him this year's version was going to be "lethal," according to my doctor. My doctor told me to not get a vaccine until very, very late fall, or early winter, even though people are pushing boosters now. He said the vaccines we've already gotten are going to be completely ineffective against what we will see this winter. But he also related that she said the new vaccines they will be coming out with this winter are going to work great. However, Mayo is bracing for a bad winter due to vaccine fatigue, the feeling that people will have that they've already had four or five shots so they should be good, and the fact that the old vaccines will be worthless against the coming strain.

                              Take that for what it's worth.
                              I saw a headline earlier today that the government is getting ready to roll out COVID restrictions sometime in the not to distant future but didn’t read it or think much of it. That would line up with what you heard from your doctor. I haven’t had a booster since around Christmas 2021 but will wait until the better one comes out later in the fall to get my next one.

                              Is RSV worse than it used to be or something? I don’t ever remember hearing much about it until a year ago or so.
                              Originally posted by BobbyBrady
                              Crosby probably wouldn't even be on BC's top two lines next year

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